Quadrivial Quandary:  Logophiles, Rejoice!  Each day we give you four unusual words.  Can you fit them all in one illustrative sentence?
Quandary Resolution 4593
impregnable, perfusion, grift, serpentine

The serpentine machinations of his romantic advances, frustrated by her impregnable virtue, a dark grift he chose: replacing her insulin with GBH, he waited like a spider for the poisonous perfusion to work as all his efforts had failed.

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